OrthoXel founders co-author exciting new tibial fracture research protocol published in JB&JS

OrthoXel is thrilled to have three of its founding members’; Charles Daly, Hannah Dailey and James Harty, co-author this article published in the Journal of Bone and Joint Surgery which focuses on Virtual Mechanical Testing Based on Low-Dose Computed Tomography Scans for Tibial Fractures.

The authors have been pioneering innovative approaches to orthopaedic trauma outcomes assessment to overcome the persistent challenge of quantitative outcomes assessment which faces orthopaedic trauma.

In comparison to traditional Patient Reported Outcome Measures (PROM) and Radiographic Union Scale in Tibial (RUST) scoring, virtual mechanical testing with low-dose CT scans provides a quantitative and objective structural callus assessment that reliably predicts time to union and may enable early diagnosis of compromised healing.

Dive deeper into this thought-provoking article here

Disclosure: Funding to support study management was provided by a grant from OrthoXel, however, no OrthoXel devices were utilized in this study.

Fig. 1

Figs. 1-A through 1-F Workflow for virtual mechanical testing. Fig. 1-A Sagittal slice view of a low-dose CT scan without masks applied. Fig. 1-B Density-based threshold masks applied for cortical bone (yellow, 1,400 to 2,700 HU) and callus (cyan, 400 to 1,400 HU). Fig. 1-C 3D reconstruction after surface optimization. Fig. 1-D 3D tetrahedral volumetric model discretization with elementwise mechanical properties derived from voxel radiodensity. Fig. 1-E Virtual torsion test with the distal end clamped and the proximal end rotated about the anatomic axis of the tibia. Fig. 1-F Reconstructed intact tibia for comparison with the VTR of the fractured bone.